A Short Guide To Uses And Procedures

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Miconazole nitrate is one of first lines of defense towards any kind of fungal infection and it is very, very effective. Fungal infections are very common during the rainy season but thankfully, catching them early means that you can treat them quickly as well.

 fungal infection

Face fungal infection.

Miconazole nitrate 2 % antifungal cream is readily available in several formulations and to help you out, we’ve created a short guide that should prove helpful.

Chemistry

The chemical compound works by preventing the formation of ergosterol. Ergosterol is critically important to the normal functioning of a fungal cell. The compound contributes to the formation of a healthy cell membrane of a cell. The compound prevents the formation of the covering membrane and weakens the cell making it delicate and friable. Cell membranes are vitally important as they form the first defense barrier for the fungal cells. If the cell membrane is delicate, the fungal cells are susceptible to attacks from almost any predator.

picture of miconazole nitrate chemical structure

Miconazole Nitrate chemical structure.

The fungal cells disintegrate with regular use of the antifungal cream and the compound is very effective in fungal conditions like athlete’s foot, jock itch, ringworm etc. Most doctors also recommend topical application of miconazole for oral and vaginal infections as well. In the last few years, miconazole has gained dubious popularity as a hair growth aid.

There is no proof to back up this claim but topical applications of a similar chemical compound called ketoconazole has been shown to increase hair growth. As a result, the compound is under active research to ascertain its hair growth properties.

Miconazole nitrate side effects

Every chemical compound has its own side effects and micornazole is no different. Mild skin irritation and burning sensations are common. However, as compared to any other medication, this anti-fungal compound is relatively safe. It does cause minor interactions with other chemical compounds like terbinafine, some varieties of statins, anticoagulants and atypical psychotics. As a result, we recommend you check with your personal physician before you start any variety of long-term antifungal treatment.

Common formulations and brand names

Miconazole is available as a cream, ointment, gel, powder and spray in different strengths. For vaginal use, vaginal suppositories and solutions are available. Almost all formulations are of 2% strength but you may find stronger versions. However, if the infection does not resolve with a 2% formulation, we recommend you consult your physician right away. The actual brand names will vary but brand names like Monisat, Vagistat and Lotrimin are used too.

Precautions

• The medication is relatively safe but if you are pregnant or breastfeeding; you may not be able to use this cream.
• Miconazole is not for internal use. Avoid contact with eyes and oral membrane. Contact the doctor immediately in case you swallow the medication.
• The medication does not work on the scalp or fingernails.
• This antifungal location cannot be used on children younger than 2 years of age unless specifically indicated by a doctor.
• Tell your doctor if the infection returns in seven days or within 2 months. You may need a stronger medication.
• Vaginal formulations may interfere with contraception measures. For example, vaginal formulations may affect the latex in condoms, diaphragms and cervical caps and interfere with OCPs as well. Most doctors recommend you use a secondary method of contraception or restrain from sexual intercourse to prevent cross infection and pregnancy.

miconazole nitrate fungal infection treatment

Micrograph of fungal infection.

Starting antifungal treatment

Your doctor will recommend the brand name and formulation for your condition. Before use, read the manufacturer’s instructions carefully. For skin infections, apply the lotion, gel or cream to the affected area twice daily. Wash your hands before and after using the medication. Continue using the medication for 10 days after the symptoms have resolved. Fungal infections are persistent and using the medication continuously will ensure that it does not return. You may also have to use secondary antifungal measures like increased exercise, improved diet and lifestyle changes to control existing medical conditions. For example, diabetes can contribute to regular fungal infections. Your doctor may increase your antidiabetic medication to bring your health and blood sugar under control to indirectly control the fungal infection as well.

Most patients see an improvement in 10 — 15 days. However, if the infection does not clear up, check with your doctor immediately.